Staff Scientist II

Company: The University Of Chicago
Location: Chicago
Posted on: April 24, 2025

Job Description:

DepartmentBSD OBG - Lengyel LabAbout the DepartmentThe Kenny/Lengyel laboratory is part of the Department of Obstetrics and Gynecology/ Section of Gynecologic Oncology, studying the biology of ovarian cancer. The laboratory has about 15 members investigating the role of metabolism and methyltransferases in ovarian cancer metastasis. We use a variety of cutting-edge methods, including spatial proteomics, spatial metabolomics, 3D organotypic cultures of human tissue, spatiotemporal characterization of the immune system, and stable-isotope tracing in patients. Bioinformatic support and access to all Core facilities at the University of Chicago are available in the laboratory. We develop novel inhibitors to treat cancer and study biomarkers to diagnose ovarian cancer and detect ovarian cancer early.Our translational research laboratory is in the Center for Integrated Science, a research building on campus that houses 40 independent research groups. This at-will position is wholly or partially funded by contractual grant funding, which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.Job SummaryThe job facilitates and promotes a research project or contributes to the scientific direction of a research resource. Receives a moderate level of guidance and direction.The focus of the job is to oversee a subgroup in the laboratory dedicated to developing inhibitors for clinical testing. The overall goal is to develop an IND application for clinical testing. The applicant will participate in grant writing, represent the laboratory at conferences, and provide project management for translational projects that lead to clinical testing of agents and methods developed in the laboratory.Responsibilities

• Supervise new laboratory personnel in the development subgroup.
• Lead collaborative efforts to optimize experimental techniques for inhibitor and biomarker characterization.
• Oversee standard operating procedures and assess quality control measures to ensure high-quality experiments that meet quality standards for IND submission.
• Serve as the lead contact for collaborations with CRO's and outside institutions for inhibitor testing.
• Manage collection and analysis of complex experimental datasets, including but not limited to clinical data, omic datasets, longitudinal studies, PK/PD studies and other types of quantitative or qualitative data as needed for a pre-IND or IND development.
• Compliance of research activities with institutional, state, and federal regulatory policies.
• Support the scientific writing of protocols (IRB), publications, and grants (both federal and non-federal).
• Contribute to proofreading, and fact-checking papers, grants, and presentations.
• Write clinical study protocols, including study design, consent forms, schema, study flyers, and amendments.
• Make SOP for sample collection progress reports (acquisition, overview, distribution of histologies, and other factors as needed/ appropriate).
• Report study enrollment on human subject research in accordance with NIH and FDA guidelines in preparation for FDA submission.
• Reviews laboratory protocols and training on new techniques. Manage complex data sets for research.
• Trains new laboratory personnel.
• Performs other related work as needed.Minimum QualificationsEducation: Minimum requirements include a PhD in related field.Work Experience: Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline.Certifications:---Preferred QualificationsEducation:
  • PhD, MD, or equivalent doctoral degree and experience with pre-clinical and clinical studies.Experience:
    • Five years or more of relevant research experience.
    • A background in toxicology studies, clinical protocol development and execution.
    • Basic statistics.
    • Experience with databases.
    • Quality control.
    • Developing standard operating procedures.Preferred Competencies
      • Knowledge in one or more relevant scientific fields.
      • Proficient in research techniques or methods.
      • Knowledge of regulatory policies and procedures.
      • Analytical skills.
      • Problem-solving skills.
      • Attention to detail.
      • Organizational skills.
      • Verbal and written communication skills.
      • Work independently and as part of a team.
      • Proficient in Microsoft Office.Working Conditions
        • Lab environment.Application Documents
          • Resume (required)
          • Cover Letter (preferred)When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.Job FamilyResearchRole ImpactIndividual ContributorScheduled Weekly Hours10Drug Test RequiredYesHealth Screen RequiredYesMotor Vehicle Record Inquiry RequiredNoPay Rate TypeHourlyFLSA StatusNon-ExemptPay Range$33.65 - $43.26The included pay rate or range represents the University's good faith estimate of the possible compensation offer for this role at the time of posting.Benefits EligibleThis position is not eligible for benefits.Posting StatementThe University of Chicago is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, or expression, national or ethnic origin, shared ancestry, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: .Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
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Keywords: The University Of Chicago, Milwaukee , Staff Scientist II, Other , Chicago, Wisconsin